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2021 1

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Antibody therapy 1

Complex membrane protein 1

Drug discovery 1

GPCRs 1

Ion channels 1

Membrane-bound enzymes 1

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Antibody Therapies Targeting Complex Membrane Proteins Review

Georgina To´a Salazar, Ziyi Huang, Ningyan Zhang, Xue-Guang Zhang, Zhiqiang An,

Engineering 2021, Volume 7, Issue 11,   Pages 1541-1551 doi: 10.1016/j.eng.2020.11.013

Abstract: of protein families that may serve as drug targets, membrane-associated G-protein-coupled receptors (GPCRsrareness of such ideal conditions is illustrated by the limited number of approved biologics for targeting GPCRsChallenges in developing antibodies to complex membrane proteins such as GPCRs, ion channels, transporters

Keywords： Antibody therapy     Complex membrane protein     Ion channels     Transporters     Membrane-bound enzymes     GPCRs    

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Antibody Therapies Targeting Complex Membrane Proteins

Georgina To´a Salazar, Ziyi Huang, Ningyan Zhang, Xue-Guang Zhang, Zhiqiang An,

Journal Article